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Consider a standing desk so your legs have constant range of motion and you are able to shift your body more frequently.
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If seated at a traditional desk chair, check that the seat height is appropriate. Feet should rest comfortably flat on the floor with knees and hips able to bend easily at 90-degree angles.
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At least once every hour, stand up and take a quick lap around your office floor and/or do some stretching—like reaching arms high up above your head or extending them out to the sides for several counts.
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Organize “walking” meetings with colleagues, or use a mobile headset if it’s just you on a training or conference call. Walk up and down halls, stairwells, or even parking lots and garages.
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Try some easy exercises at your desk when you feel tension setting in, such as shoulder shrugs, neck rolls, torso twists, or seated leg extensions.